Tuberculosis in Vaccinated versus Unvaccinated Children with BCG Vaccine in Niamey: Epidemiological, Diagnostic and Outcome Aspects

Introduction: Tuberculosis remains a public health problem worldwide. The BCG vaccination is one of response means. objective this work was to study impact on morbidity and mortality related childhood tuberculosis in Niamey. Patients methods: It multicenter prospective comparative from January September 2017 two-referral hospital centers Niamey the National Anti-Tuberculosis Center. population consisted exhaustively children aged 0 15 years old suffering tuberculosis. Epidemiological, diagnostic evolving aspects vaccinated unvaccinated were studied. Statistical tests used Pearson's Chi² Fisher's exact test (p <0.05). Results: Ninety-one rate 60.4%. mean age 6 11 months [3 months-15 years]. Children under 2 less affected (11%) than (3.2%). No association found between duration signs = 0.37), expression tuberculin skin 0.43), children's status. On other hand, there significant link status results microscopic examination sputum or gastric fluid 0.02), occurrence complications 0.014) death risk 0.003). Conclusion: This shows that children’s interferes with some Therefore, fighting against must be intensified, through combination many strategies including vaccination.